L2

1. Basic Information

• Product Name : LL37 Peptide
• Category : Human Antimicrobial Peptide (Cathelicidin Family)
• Specification : 5mg/vial (Lyophilized Powder. with dextran as excipient)

2. Physical Properties

• Appearance : White to off-white lyophilized powder
• Solubility : Easily dissolves in sterile water or PBS buffer (pH 7.2–7.4; recommended concentration ≥20μg/ml)

3. Research Applications

Exclusively for laboratory research (not for clinical/human/animal use). Supports studies in:

• Antibacterial mechanisms (against Staphylococcus aureus . Escherichia coli . Candida albicans . etc.).
• Immunomodulation & inflammatory responses (e.g.. NF-κB signaling pathway. macrophage polarization).
• Tissue repair (epithelial cell migration. angiogenesis in wound/mucosal repair models).
• Tumor microenvironment (tumor cell proliferation/invasion. tumor-associated macrophage phenotype).

4. Storage & Handling

• Unopened : Store at 2–8℃ (light-protected); for long-term storage. use -20℃ or lower.
• After Reconstitution : Stable for 2–3 days at 4℃; aliquot and freeze at -20℃ to extend validity to 1–2 months (avoid repeated freeze-thaw cycles).
• Safety : Handle with gloves/goggles in a fume hood (prevent powder inhalation or skin/mucous membrane contact).

5. Compliance & Quality

• Regulatory : Must comply with target market regulations (e.g.. FDA’s research substance management in the US. EU’s Biocidal Products Regulation for peptide-related research).
• Quality Assurance : Purity ≥95% (tested via HPLC); endotoxin <1EU/μg (tested via LAL method); manufactured under GMP standards.